盐酸头孢卡品酯的基本信息

【通用名】盐酸头孢卡品酯

【英文名】cefcapene pivoxil hydrochloride

【商品名】Flomox

【中文别名】 7-[2-(2-氨基-1,3-噻唑-4-基)戊-3-烯酰胺基]-3-(氨基甲酰氧甲基)-8-氧代-5-硫-1-氮杂双环[4.2.0]辛-2-烯-2-甲酸2,2-二甲基丙酰氧甲基酯盐酸盐

【英文别名】 2,2-dimethylpropanoyloxymethyl 7-[2-(2-amino-1,3-thiazol-4-yl)pent-2-enoylamino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylateCEFCAPENE PIVOXIL HCL(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, (2,2-Dimethyl-1-oxopropoxy)methyl Ester HydrochlorideFlomoxCefcapene[(2,2-dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino}-3-[(carbamoyloxy)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride[(2,2-dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino}-3-[(carbamoyloxy)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride hydrate

【CAS】

135889-00-8 (cefcapene)

105889-45-0 (cefcapene pivoxil)

147816-23-7 (anhydrous cefcapene pivoxil hydrochloride)

147816-24-8 (cefcapene pivoxil hydrochloride)

【分子式】C23H29N5O8S2,HCl,H2O

【分子量】 622.11

【化学名】

Pivaloyloxymethyl (+)-(6R,7R)-7-[(Z)-2-(2-amino-4-thiazolyl)-2-pentenamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid carbamate monohydrochloride monohydrate

【开发单位】盐野义制药株式会社

【剂型】片剂

【规格】75mg，100mg

【用法用量】口服75mg、150mg

【临床试验】

对153例患者，每天200-600mg、28d，临床有效率胆道感染为95%，急性乳腺炎100%，伤口感染80%，其他皮肤感染80。