乙二醇二甲醚的环境影响

中文别名：一甲基二乙二醇醚

英文别名：Diethyleneglycolmonomethylether，Methylcarbitol，Methyldigol，2-(2-Methyloxyethoxy)ethanol 无色液体。有芳香气味。有吸湿性。能与水、乙醇、甘油、乙醚、丙酮、二甲基乙酰胺等混溶。相对密度(d204)1.035。熔点<-84℃。沸点193℃。折光率(n27D)1.4264。闪点93℃。半数致死量(大鼠，经口)9.21g/kg。有刺激性。

呵呵。不过上述三个物质的毒性类似，均与二乙二醇的毒性直接相关。

二乙二醇可以被人体吸收，并在体内降解为2个乙二醇，从而走乙二醇分解吸收的路线。

乙二醇在体内，对人的肝脏、肾脏功能损害严重。属于有毒物质。

所以你问的问题也是有毒的。但是从毒理学角度，它仅对人体有较大毒害，对一般实验用的小白鼠、家兔等毒性表现不明显。

1.用作硝酸纤维素、树脂等的溶剂以及制备碱金属氧化物、硼烷时的溶剂。萘、联苯、三联苯、蒽等芳香烃在乙二醇二甲醚中与钠生成络合物。钠-萘络合物在聚四氟乙烯等含氟树脂黏合时用于表面处理。钠-联苯络合物用于汽油中的卤素测定。还可用于从稀乙酸水溶液中回收乙酸。也用于脱漆剂、稀释剂及增加润滑油的黏度等。

2.用作溶剂。用于电化学分析。

乙二醇二甲醚*危险性概述

危险性类别：第3.2类 中闪点液体

侵入途径： 吸入、食入

健康危害： 口服引起恶心、呕吐、腹绞痛、虚弱、昏迷。具有刺激性。

环境危害： 对环境有害。

燃爆危险： 易燃，其蒸气与空气混合，能形成爆炸性混合物。

乙二醇二甲醚*急救措施

皮肤接触： 脱去污染的衣着，用肥皂水和清水彻底冲洗皮肤。如有不适感，就医。

眼睛接触： 提起眼睑，用流动清水或生理盐水冲洗。如有不适感，就医。

吸入： 迅速脱离现场至空气新鲜处。保持呼吸道通畅。如呼吸困难，给输氧。呼吸、心跳停止，立即进行心肺复苏术。就医。

食入： 饮水，禁止催吐。如有不适感，就医。

乙二醇二甲醚*消防措施

危险特性： 易燃，遇明火、高热易引起燃烧爆炸。与氧化剂能发生强烈反应。接触空气或在光照条件下可生成具有潜在爆炸危险性的过氧化物。蒸气比空气重，沿地面扩散并易积存于低洼处，遇火源会着火回燃。

有害燃烧产物：一氧化碳。

灭火方法： 用抗溶性泡沫、干粉、二氧化碳、砂土灭火。

灭火注意事项及措施：消防人员须佩戴防毒面具、穿全身消防服，在上风向灭火。尽可能将容器从火场移至空旷处。喷水保持火场容器冷却，直至灭火结束。处在火场中的容器若已变色或从安全泄压装置中产生声音，必须马上撤离。

乙二醇二甲醚*泄漏应急处理

泄漏处理与废弃:

去除着火源。

考虑撤离所有人员。

防止进入排水沟。

用任何可能的方法收客泄漏物。

用喷水或水雾来控制气体。

用干燥的介质吸收。

在安全的情况下, 堵漏。

本物质及其容器必须用安全的方法销毁。

用水清洁地板以及所有被本物质污染的东西。

乙二醇二甲醚*操作处置

操作注意事项：密闭操作，全面通风。操作人员必须经过专门培训，严格遵守操作规程。建议操作人员佩戴过滤式防毒面具(半面罩)，戴化学安全防护眼镜，穿防静电工作服，戴橡胶耐油手套。远离火种、热源，工作场所严禁吸烟。使用防爆型的通风系统和设备。防止蒸气泄漏到工作场所空气中。避免与氧化剂、酸类接触。灌装时应控制流速，且有接地装置，防止静电积聚。搬运时要轻装轻卸，防止包装及容器损坏。配备相应品种和数量的消防器材及泄漏应急处理设备。倒空的容器可能残留有害物。

乙二醇二甲醚*接触控制/个体防护

工程控制： 生产过程密闭，全面通风。提供安全淋浴和洗眼设备。

呼吸系统防护：高浓度蒸气接触可佩戴过滤式防毒面具(半面罩)。

眼睛防护： 一般不需要特殊防护，高浓度接触时可戴化学安全防护眼镜。

身体防护： 穿防静电工作服。

手 防 护：戴橡胶耐油手套。

其他防护： 工作现场禁止吸烟、进食和饮水。工作完毕，淋浴更衣。注意个人清洁卫生。

乙二醇二甲醚*废弃处置

废弃物性质：危险废物 废弃

废弃处置方法：建议用焚烧法处置。

废弃注意事项：处置前应参阅国家和地方有关法规。

乙二醇二甲醚*运输信息

危险货物编号： 32093

UN编号： 2252

包装类别： Ⅱ类包装

包装标志： 易燃液体

包装方法： 安瓿瓶外普通木箱螺纹口玻璃瓶、铁盖压口玻璃瓶、塑料瓶或金属桶(罐)外普通木箱。

运输注意事项：运输时运输车辆应配备相应品种和数量的消防器材及泄漏应急处理设备。夏季最好早晚运输。运输时所用的槽(罐)车应有接地链，槽内可设孔隔板以减少震荡产生静电。严禁与氧化剂、酸类、食用化学品、等混装混运。运输途中应防曝晒、雨淋，防高温。中途停留时应远离火种、热源、高温区。装运该物品的车辆排气管必须配备阻火装置，禁止使用易产生火花的机械设备和工具装卸。公路运输时要按规定路线行驶，勿在居民区和人口稠密区停留。铁路运输时要禁止溜放。严禁用木船、水泥船散装运输。

　乙二醇二甲醚*贮存方法

1.储存于阴凉、干燥、通风的库房，远离火种，防静电。保持容器密封，储存的地方远离氧化剂，远离热力和直接阳光照射。

2.应备有防爆，泄漏应急处理设备和合适的收容材料。

3.通常商品加有稳定剂。储存于阴凉、通风的库房。远离火种、热源。库温不宜超过37℃，包装要求密封，不可与空气接触。应与氧化剂、酸类分开存放，切忌混储。采用防爆型照明、通风设施。禁止使用易产生火花的机械设备和工具。

沸点

84-86 ºC  

乙二醇二甲醚中文别名:二甲基溶纤剂1,2-二甲氧基乙烷1,2-二甲氧基代乙烷1,2-二甲基乙烷

图一

是一种带有醚味的水白色中性液体，性质稳定，不易发生反应，能溶解各种树脂和纤维素，并能与水和许多醇，酮，酯等有机溶剂以任意比例混溶，其溶解能力可以通过水或某些溶剂作适当稀释来调节。

图二

危险特性:易燃，遇明火、高热易引起燃烧爆炸。与氧化剂能发生强烈反应。接触空气或在光照条件下可生成具有潜在爆炸危险性的过氧化物。其蒸气比空气重，能在较低处扩散到相当远的地方，遇明火会引着回燃。

乙二醇二甲醚属于3类危险品，易燃液体。

编号 毒性类型 测试方法 测试对象 使用剂量 毒性作用 1 acute Oral Human 3380 mg/kg 1.胃肠道毒性Gastrointestinal - gastritis2.肝毒性Liver - other changes3.肾、输尿管和膀胱毒性Kidney, Ureter, Bladder -other changes 2 acute Inhalation Human 25 ppm 1.行为毒性Behavioral - tremor2.行为毒性Behavioral - convulsions or effect on seizure threshold3.行为毒性Behavioral - changes in motor activity (specific assay) 3 acute Oral Rodent - rat 2370 mg/kg 1.行为毒性Behavioral - altered sleep time (including change in righting reflex)2.肺部、胸部或者呼吸毒性Lungs, Thorax, or Respiration -other changes 4 acute Inhalation Rodent - rat 1500 ppm/7H 1.Details of toxic effects not reported other than lethal dose value 5 acute Intraperitoneal Rodent - rat 2500 mg/kg 1.Details of toxic effects not reported other than lethal dose value 6 acute Intravenous Rodent - rat 2068 mg/kg 1.血液毒性Blood - other hemolysis with or without anemia 7 acute Oral Rodent - mouse 2560 mg/kg 1.行为毒性Behavioral - somnolence (general depressed activity)2.行为毒性Behavioral - changes in motor activity (specific assay)3.心脏毒性Cardiac - other changes 8 acute Inhalation Rodent - mouse 1480 ppm/7H 1.行为毒性Behavioral - analgesia2.肺部、胸部或者呼吸毒性Lungs, Thorax, or Respiration -dyspnea3.肾、输尿管和膀胱毒性Kidney, Ureter, Bladder -hematuria 9 acute Intraperitoneal Rodent - mouse 2147 mg/kg 1.肾、输尿管和膀胱毒性Kidney, Ureter, Bladder -changes in both tubules and glomeruli2.血液毒性Blood - changes in spleen3.血液毒性Blood - other changes 10 acute Oral Rodent - rabbit 890 mg/kg 1.行为毒性Behavioral - general anesthetic2.血液毒性Blood - other hemolysis with or without anemia 11 acute Administration onto the skin Rodent - rabbit 1280 mg/kg 1.Details of toxic effects not reported other than lethal dose value 12 acute Oral Rodent - guinea pig 950 mg/kg 1.行为毒性Behavioral - general anesthetic2.胃肠道毒性Gastrointestinal - other changes3.肾、输尿管和膀胱毒性Kidney, Ureter, Bladder -other changes 13 MutipleDose Inhalation Rodent - rat 400 ppm/6H/2W-I 1.大脑毒性Brain and Coverings - other degenerative changes2.营养和代谢系统毒性Nutritional and Gross Metabolic - weight loss or decreased weight gain3.生化毒性Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - multiple enzyme effects 14 MutipleDose Oral Rodent - rat 10206 mg/kg/21D-C 1.内分泌毒性Endocrine - changes in thymus weight2.营养和代谢系统毒性Nutritional and Gross Metabolic - weight loss or decreased weight gain3.慢性病相关毒性Related to Chronic Data - changes in testicular weight 15 MutipleDose Oral Rodent - rat 500 mg/kg/10D-I 1.内分泌毒性Endocrine - changes in thymus weight2.免疫系统毒性Immunological Including Allergic - decreased immune response 16 MutipleDose Inhalation Rodent - rat 300 ppm/6H/13W-I 1.血液毒性Blood - changes in leukocyte (WBC) count2.营养和代谢系统毒性Nutritional and Gross Metabolic - weight loss or decreased weight gain3.慢性病相关毒性Related to Chronic Data - changes in testicular weight 17 MutipleDose Inhalation Rodent - rat 970 mg/m3/7H/5W-I 1.血液毒性Blood - changes in bone marrow (not otherwise specified)2.血液毒性Blood - changes in spleen 18 MutipleDose Inhalation Rodent - rat 1000 ppm/6H/11D-I 1.肾、输尿管和膀胱毒性Kidney, Ureter, Bladder -other changes in urine composition2.血液毒性Blood - changes in bone marrow (not otherwise specified)3.血液毒性Blood - changes in leukocyte (WBC) count 19 MutipleDose Administration onto the skin Rodent - rat 20 mg/kg/4W-I 1.血液毒性Blood - changes in other cell count (unspecified)2.血液毒性Blood - changes in leukocyte (WBC) count3.慢性病相关毒性Related to Chronic Data - changes in testicular weight 20 MutipleDose Intraperitoneal Rodent - rat 450 mg/kg/16D-I 1.血液毒性Blood - changes in other cell count (unspecified)2.生化毒性Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes 21 MutipleDose Oral Rodent - rat 29484 mg/kg/13W-C 1.内分泌毒性Endocrine - changes in thymus weight2.血液毒性Blood - changes in platelet count3.营养和代谢系统毒性Nutritional and Gross Metabolic - weight loss or decreased weight gain 22 MutipleDose Administration onto the skin Rodent - rat 3200 mg/kg/4D-I 1.内分泌毒性Endocrine - changes in thymus weight2.免疫系统毒性Immunological Including Allergic - decrease in humoral immune response 23 MutipleDose Oral Rodent - mouse 12110 mg/kg/2W-C 1.内分泌毒性Endocrine - changes in thymus weight2.慢性病相关毒性Related to Chronic Data - changes in testicular weight 24 MutipleDose Oral Rodent - mouse 82 mg/kg/13W-C 1.内分泌毒性Endocrine - effect on menstrual cycle2.内分泌毒性Endocrine - other changes3.血液毒性Blood - changes in spleen 25 MutipleDose Inhalation Rodent - mouse 1000 ppm/6H/11D-I 1.血液毒性Blood - changes in leukocyte (WBC) count2.慢性病相关毒性Related to Chronic Data - changes in testicular weight 26 MutipleDose Inhalation Mammal - dog 750 ppm/7H/12W-I 1.血液毒性Blood - microcytosis with or without anemia2.血液毒性Blood - other changes 27 MutipleDose Inhalation Rodent - rabbit 300 ppm/6H/13W-I 1.内分泌毒性Endocrine - changes in thymus weight2.血液毒性Blood - changes in erythrocyte (RBC) count3.慢性病相关毒性Related to Chronic Data - changes in testicular weight 28 MutipleDose Administration onto the skin Rodent - guinea pig 65 mg/kg/13W-I 1.血液毒性Blood - changes in erythrocyte (RBC) count2.营养和代谢系统毒性Nutritional and Gross Metabolic - weight loss or decreased weight gain3.慢性病相关毒性Related to Chronic Data - changes in testicular weight 29 SkinEyeIrrition Administration onto the skin Rodent - rabbit 483 mg/24H 1.Mild 30 SkinEyeIrrition Administration into the eye Rodent - rabbit 97 mg 31 SkinEyeIrrition Administration into the eye Rodent - rabbit 500 mg/24H 1.Mild 32 SkinEyeIrrition Administration into the eye Rodent - guinea pig 10 ug 1.Mild 33 Mutation Human Lymphocyte 150 mmol/L 34 Mutation Oral Rodent - rat 500 mg/kg 35 Mutation Oral Rodent - rat 500 mg/kg 36 Mutation Oral Rodent - mouse 500 mg/kg 37 Reproductive Oral Rodent - rat 175 mg/kg,female 7-13 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -cardiovascular (circulatory) system 38 Reproductive Oral Rodent - rat 175 mg/kg,female 7-13 day(s) after conception 1.生殖毒性Reproductive - Maternal Effects - parturition2.生殖毒性Reproductive - Effects on Newborn -biochemical and metabolic 39 Reproductive Oral Rodent - rat 15015 mg/kg,male 13 week(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, andcount) 40 Reproductive Oral Rodent - rat 100 mg/kg,male 1 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 41 Reproductive Oral Rodent - rat 350 mg/kg,female 9-15 day(s) after conception 1.生殖毒性Reproductive - Fertility -litter size (e.g. # fetuses per littermeasured before birth)2.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus)3.生殖毒性Reproductive - Specific Developmental Abnormalities -cardiovascular (circulatory) system 42 Reproductive Inhalation Rodent - rat 68 mg/kg/4H,female 1-19 day(s) after conception 1.生殖毒性Reproductive - Fertility -pre-implantation mortality (e.g. reduction in number of implants per femaletotal number of implants per corpora lutea)2.生殖毒性Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) 43 Reproductive Inhalation Rodent - rat 30 ppm/6H,male 65 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 44 Reproductive Inhalation Rodent - rat 100 ppm/6H,female 6-17 day(s) after conception 1.生殖毒性Reproductive - Maternal Effects - parturition2.生殖毒性Reproductive - Fertility -female fertility index (e.g. # females pregnant per # sperm positive females# females pregnant per # femalesmated)3.生殖毒性Reproductive- Effects on Newborn -live birth index (measured after birth) 45 Reproductive Inhalation Rodent - rat 100 ppm/6H,female 6-17 day(s) after conception 1.生殖毒性Reproductive - Effects on Newborn -viability index (e.g., # alive at day 4 per # bornalive)2.生殖毒性Reproductive - Effects on Newborn -growth statistics (e.g.%, reduced weight gain) 46 Reproductive Inhalation Rodent - rat 30 ppm/6H,male 13 week(s) pre-mating 1.生殖毒性Reproductive - Fertility -post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) 47 Reproductive Administration onto the skin Rodent - rat 11592 mg/kg,female 6-17 day(s) after conception 1.生殖毒性Reproductive - Fertility -female fertility index (e.g. # females pregnant per # sperm positive females# females pregnant per # femalesmated)2.生殖毒性Reproductive - Effects on Embryo or Fetus - fetaldeath 48 Reproductive Administration onto the skin Rodent - rat 4375 mg/kg,male 7 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, andcount)2.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct3.生殖毒性Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females) 49 Reproductive Administration onto the skin Rodent - rat 2 mg/kg,female 10 day(s) after conception 1.生殖毒性Reproductive - Fertility -post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) 50 Reproductive Administration onto the skin Rodent - rat 1 mg/kg,female 12 day(s) after conception 1.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus)2.生殖毒性Reproductive - Specific Developmental Abnormalities -craniofacial (including nose andtongue)3.生殖毒性Reproductive - Specific Developmental Abnormalities -gastrointestinal system 51 Reproductive Intraperitoneal Rodent - rat 330 mg/kg,female 12 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system2.生殖毒性Reproductive - Specific Developmental Abnormalities -cardiovascular (circulatory) system 52 Reproductive Intraperitoneal Rodent - rat 190 mg/kg,female 14 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -Central Nervous System2.生殖毒性Reproductive - Specific Developmental Abnormalities -urogenital system 53 Reproductive Intraperitoneal Rodent - rat 190 mg/kg,female 12 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system 54 Reproductive Intraperitoneal Rodent - rat 190 mg/kg,female 8 day(s) after conception 1.生殖毒性Reproductive - Fertility -post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) 55 Reproductive Subcutaneous Rodent - rat 600 mg/kg,female 6-20 day(s) after conception 1.生殖毒性Reproductive- Effects on Newborn -live birth index (measured after birth)2.生殖毒性Reproductive - Effects on Newborn -viability index (e.g., # alive at day 4 per # bornalive) 56 Reproductive Subcutaneous Rodent - rat 440 mg/kg,female 7-17 day(s) after conception 1.生殖毒性Reproductive- Effects on Newborn -live birth index (measured after birth) 57 Reproductive Oral Rodent - rat 250 mg/kg,female 13 day(s) after conception 1.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus)2.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system 58 Reproductive Oral Rodent - mouse 175 mg/kg,female 11 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system 59 Reproductive Oral Rodent - mouse 2 mg/kg,female 7-14 day(s) after conception 1.生殖毒性Reproductive - Fertility -litter size (e.g. # fetuses per littermeasured before birth)2.生殖毒性Reproductive - Effects on Embryo or Fetus - fetaldeath3.生殖毒性Reproductive - Specific Developmental Abnormalities -Central Nervous System 60 Reproductive Oral Rodent - mouse 500 mg/kg,female 9 day(s) after conception 1.生殖毒性Reproductive - Fertility -post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)2.生殖毒性Reproductive - Fertility - litter size (e.g. # fetuses per littermeasured before birth)3.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus) 61 Reproductive Oral Rodent - mouse 250 mg/kg,female 11 day(s) after conception 1.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus)2.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system 62 Reproductive Oral Rodent - mouse 6250 mg/kg,male 25 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 63 Reproductive Inhalation Rodent - mouse 1000 ppm/6H,male 11 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 64 Reproductive Inhalation Rodent - mouse 500 ppm/7H,male 5 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, andcount) 65 Reproductive Inhalation Rodent - mouse 50 ppm/6H,female 6-15 day(s) after conception 1.生殖毒性Reproductive - Fertility -litter size (e.g. # fetuses per littermeasured before birth)2.生殖毒性Reproductive - Specific Developmental Abnormalities -urogenital system 66 Reproductive Inhalation Rodent - mouse 50 ppm/6H,female 6-15 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system2.生殖毒性Reproductive - Specific Developmental Abnormalities -urogenital system 67 Reproductive Subcutaneous Rodent - mouse 1200 mg/kg,female 7-13 day(s) after conception 1.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus) 68 Reproductive Subcutaneous Rodent - mouse 3200 mg/kg,female 7-14 day(s) after conception 1.生殖毒性Reproductive - Fertility -post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) 69 Reproductive Subcutaneous Rodent - mouse 250 mg/kg,female 8 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -Central Nervous System2.生殖毒性Reproductive - Specific Developmental Abnormalities -craniofacial (including nose andtongue) 70 Reproductive Intravenous Rodent - mouse 250 mg/kg,female 8 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -Central Nervous System 71 Reproductive Oral Primate - monkey 930 mg/kg,female 20-45 day(s) after conception 1.生殖毒性Reproductive - Fertility -abortion2.生殖毒性Reproductive - Effects on Embryo or Fetus - fetaldeath 72 Reproductive Oral Primate - monkey 633 mg/kg,female 20-45 day(s) after conception 1.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus) 73 Reproductive Inhalation Rodent - rabbit 300 ppm/6H,male 65 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 74 Reproductive Inhalation Rodent - rabbit 50 ppm/6H,female 6-18 day(s) after conception 1.生殖毒性Reproductive - Specific Developmental Abnormalities -body wall2.生殖毒性Reproductive - Specific Developmental Abnormalities -cardiovascular (circulatory) system3.生殖毒性Reproductive - Specific Developmental Abnormalities -urogenital system 75 Reproductive Inhalation Rodent - rabbit 50 ppm/6H,female 6-18 day(s) after conception 1.生殖毒性Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stuntedfetus)2.生殖毒性Reproductive - Specific Developmental Abnormalities -body wall3.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system 76 Reproductive Inhalation Rodent - rabbit 10 ppm/6H,female 6-18 day(s) after conception 1.生殖毒性Reproductive - Fertility -post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)2.生殖毒性Reproductive - Specific Developmental Abnormalities -musculoskeletal system 77 Reproductive Oral Rodent - guinea pig 6250 mg/kg,male 25 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 78 Reproductive Administration onto the skin Rodent - guinea pig 65 mg/kg,male 65 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct 79 Reproductive Oral Rodent - hamster 1562 mg/kg,male 25 day(s) pre-mating 1.生殖毒性Reproductive - Paternal Effects - testes, epididymis, spermduct