氨基胍硝酸盐的合成路线有哪些

基本信息：

中文名称

(5-氨基-4H-[1,2,4]噻唑-3-基)-乙酸

中文别名

(5-氨基-1H-1,2,4-三唑-3-基)乙酸

英文名称

2-(3-amino-1H-1,2,4-triazol-5-yl)acetic

acid

英文别名

1h-1,2,4-triazole-3-acetic

acid,5-amino5-amino-1,2,4-triazol-3-ylacetic

acid(3-Amino-1H-1,2,4-triazol-5-yl)acetic

acidaminotriazolylaceticacid(5-amino-1H-1,2,4-triazol-3-yl)acetic

acid(5-amino-4h-1,2,4-triazol-3-yl)acetic

acid5-amino-1H-1,2,4-triazole-3-acetic

acid

CAS号

143832-52-4

上游原料

CAS号

中文名称

141-82-2

丙二酸

2200-97-7

氨基胍碳酸氢盐

79-17-4

氨基胍媒染剂

2582-30-1

氨基胍碳酸氢盐

下游产品

CAS号

名称

143832-52-4

(5-氨基-4H-[1,2,4]噻唑-3-基)-乙酸

更多上下游产品参见：http://baike.molbase.cn/cidian/1525431

中文名称

3,5-二甲基吡唑-1-硝酸咪

中文别名

3,5-二甲基吡唑-1-甲脒硝酸盐

英文名称

3,5-Dimethylpyrazole-1-carboxamidine

nitrate

英文别名

3,5-DIMETHYLPYRAZOLE-1-CARBOXAMIDINE

NITRATE3,5-Dimethyl-1-pyrazolylformaminidium

nitrate3,5-Dimethylpyrazole-1-Carboxamidine

Nitrate

CAS号

38184-47-3

合成路线：

1.通过氨基胍硝酸盐和乙酰丙酮合成3,5-二甲基吡唑-1-硝酸咪，收率约49%；

更多路线和参考文献可参考http://baike.molbase.cn/cidian/29744

Aminoguanidine bicarbonate

【Synonyms】

2-Aminouanidine bicarbonate

Aminoguanidinium bicarbonate

Carbonic acid, compound with hydrazinecarboximidamide (1:1)

【CAS】

2582-30-1

【Formula】

C2H8N4O3

【Molecular Weight】

136.11000000000001

【EINECS】

219-956-7

【RTECS】

FG1772000

【RTECS Class】

Other

【Beilstein/Gmelin】

3569869

【Beilstein Reference】

4-03-00-00236

【EC Class】

sensitizing, dangerous for the environment

Physical and Chemical PropertiesBack to Contents

【Appearance】

White crystalline powder.

【Solubility in water】

3.3 g/L (30 C)

【Melting Point】

125

【Density】

1.600 g/cm3 (20 C)

【Vapor Density】

4.7

First Aid MeasuresBack to Contents

【Ingestion】

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and StorageBack to Contents

【Storage】

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

【Handling】

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse. Discard contaminated shoes.

Hazards IdentificationBack to Contents

【Inhalation】

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

【Skin】

Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.

【Eyes】

Causes eye irritation.

【Ingestion】

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

【EC Risk Phrase】

R 43

【EC Safety Phrase】

S 22 36/37

【UN (DOT)】

3335

Exposure Controls/Personal ProtectionBack to Contents

【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

【Exposure Effects】

Repeated or prolonged exposure may cause allergic reactions in sensitive individuals.

Fire Fighting MeasuresBack to Contents

【Autoignition】

245

【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release MeasuresBack to Contents

【Small spills/leaks】

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and ReactivityBack to Contents

【Disposal Code】

28

【Incompatibilities】

Oxidizing agents.

【Stability】

Stable under normal temperatures and pressures.

【Decomposition】

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Transport InformationBack to Contents

【UN Number】

3335

【HS Code】

2928 00 90

中文名称

氨基胍硝酸盐

中文别名

氨胍硝酸

英文名称

Aminoguanidinium

nitrate

英文别名

Aminoguanidine

nitrate2-aminoguanidine,nitric

acid

CAS号

10308-82-4

中国海关编码(HS-code)：29280000.90

概述：

2928000090

其他肼（联氨）及胲（羟胺）的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%.

申报要素：

品名,

成分含量,

用途.

Summary：

2928000090

other

organic

derivatives

of

hydrazine

or

of

hydroxylamine

VAT:17.0%

Tax

rebate

rate:9.0%

Supervision

conditions:none

MFN

tariff:6.5%

General

tariff:20.0%.

其他各国海关编码海关数据详见：http://baike.molbase.cn/cidian/41637